| pubmed-article:10082435 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10082435 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:10082435 | lifeskim:mentions | umls-concept:C0003873 | lld:lifeskim |
| pubmed-article:10082435 | lifeskim:mentions | umls-concept:C1415576 | lld:lifeskim |
| pubmed-article:10082435 | lifeskim:mentions | umls-concept:C0002085 | lld:lifeskim |
| pubmed-article:10082435 | lifeskim:mentions | umls-concept:C1837204 | lld:lifeskim |
| pubmed-article:10082435 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10082435 | pubmed:dateCreated | 1999-5-24 | lld:pubmed |
| pubmed-article:10082435 | pubmed:abstractText | In Sardinia, like in other Caucasoid populations, rheumatoid arthritis (RA) is significantly associated with HLA-DR4 and DR1 antigens. To discover which DR4 and DR1 alleles were associated with the disease we selected 22 Sardinian patients affected by RA. Fifty DR4+ and 28 DR1+ healthy individuals coming from the same geographical area were used as controls. In the Sardinian patients only two DRB1*04 alleles were observed: DRB1*0405 in 11 and DRB1*0403 in three patients. The DRB1*0102 allele was observed in two patients and DRB1*0101 in six patients. Hereditary predisposition to RA in Sardinia therefore seems to be almost exclusively associated with the DRB1*0405 and DRB1*0101 alleles which share the 67LLEQRRAA74-85VG86 epitope in the peptide binding groove. | lld:pubmed |
| pubmed-article:10082435 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10082435 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10082435 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10082435 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10082435 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10082435 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10082435 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10082435 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10082435 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:10082435 | pubmed:issn | 0001-2815 | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:MathieuAA | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:ContuLL | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:LalPP | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:SannaGG | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:AlbuRR | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:PassiuGG | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:CarcassiCC | lld:pubmed |
| pubmed-article:10082435 | pubmed:author | pubmed-author:CauleEE | lld:pubmed |
| pubmed-article:10082435 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10082435 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:10082435 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10082435 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10082435 | pubmed:pagination | 97-100 | lld:pubmed |
| pubmed-article:10082435 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:10082435 | pubmed:meshHeading | pubmed-meshheading:10082435... | lld:pubmed |
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| pubmed-article:10082435 | pubmed:meshHeading | pubmed-meshheading:10082435... | lld:pubmed |
| pubmed-article:10082435 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10082435 | pubmed:articleTitle | HLA-DRB1*01 and DRB1*04 alleles in Sardinian rheumatoid arthritis patients. | lld:pubmed |
| pubmed-article:10082435 | pubmed:affiliation | Cattedra di Genetica Medica, Dipartimento di Scienze Mediche, Università di Cagliari, Italy. | lld:pubmed |
| pubmed-article:10082435 | pubmed:publicationType | Journal Article | lld:pubmed |
