| pubmed-article:10078998 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0005847 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0025474 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0237743 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0042396 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0006669 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0205227 | lld:lifeskim |
| pubmed-article:10078998 | lifeskim:mentions | umls-concept:C0127400 | lld:lifeskim |
| pubmed-article:10078998 | pubmed:issue | 2-3 | lld:pubmed |
| pubmed-article:10078998 | pubmed:dateCreated | 1999-6-22 | lld:pubmed |
| pubmed-article:10078998 | pubmed:abstractText | The role of perivascular calcitonin gene-related peptide (CGRP)-containing nerves in the modulation of adrenergic nerve-mediated vasoconstrictions was studied in the rat perfused mesenteric vascular bed. A frequency-dependent vasoconstriction induced by periarterial nerve stimulation (1-6 Hz) of the bed was significantly potentiated by perfusion of 1 microM CGRP-(8-37) (CGRP receptor antagonist) or to a similar extent after treatment with 500 nM capsaicin. In the preparations treated with capsaicin, CGRP-(8-37) caused a small potentiation of periarterial nerve stimulation-induced vasoconstriction. Exogenous CGRP (0.1-1 nM) concentration-dependently attenuated the augmented vasoconstriction in response to periarterial nerve stimulation after treatment with capsaicin. However, exogenous CGRP (1 nM) did not attenuate the periarterial nerve stimulation-induced vasoconstriction in the bed untreated with capsaicin. These results suggest that endogenous CGRP, which is released from CGRP-containing nerves, suppresses the adrenergic nerve function involved in mechanisms regulating the tone of resistant blood vessels. | lld:pubmed |
| pubmed-article:10078998 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10078998 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10078998 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10078998 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10078998 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10078998 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10078998 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10078998 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10078998 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10078998 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10078998 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:10078998 | pubmed:author | pubmed-author:KawasakiHH | lld:pubmed |
| pubmed-article:10078998 | pubmed:author | pubmed-author:TakenagaMM | lld:pubmed |
| pubmed-article:10078998 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10078998 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:10078998 | pubmed:volume | 367 | lld:pubmed |
| pubmed-article:10078998 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10078998 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10078998 | pubmed:pagination | 239-45 | lld:pubmed |
| pubmed-article:10078998 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
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| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:meshHeading | pubmed-meshheading:10078998... | lld:pubmed |
| pubmed-article:10078998 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10078998 | pubmed:articleTitle | Endogenous calcitonin gene-related peptide suppresses vasoconstriction mediated by adrenergic nerves in rat mesenteric resistance blood vessels. | lld:pubmed |
| pubmed-article:10078998 | pubmed:affiliation | The First Department of Internal Medicine, Miyazaki Medical College, Japan. | lld:pubmed |
| pubmed-article:10078998 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10078998 | pubmed:publicationType | In Vitro | lld:pubmed |
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