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pubmed-article:10074465pubmed:abstractTextThe 'RNA world' hypothesis requires that RNA be able to catalyze a wide variety of chemical reactions. In vitro selection from combinatorial RNA libraries has been used to identify several catalytic activities, most of which have resulted in a self-modification of RNA at one of its constituents. The formation of carbon-carbon bonds is considered an essential prerequisite for a complex metabolism based on RNA.lld:pubmed
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pubmed-article:10074465pubmed:articleTitleA small catalytic RNA motif with Diels-Alderase activity.lld:pubmed
pubmed-article:10074465pubmed:affiliationInstitut für Biochemie der FU Berlin Thielallee 63 14195 Berlin Germany.lld:pubmed
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