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pubmed-article:10028982pubmed:abstractTextThe function of local renin-angiotensin systems in skeletal muscle and adipose tissue remains largely unknown. A polymorphism of the human angiotensin converting enzyme (ACE) gene has been identified in which the insertion (I) rather than deletion (D) allele is associated with lower ACE activity in body tissues and increased response to some aspects of physical training. We studied the association between the ACE gene insertion or deletion polymorphism and changes in body composition related to an intensive exercise programme, to investigate the metabolic effects of local human renin-angiotensin systems.lld:pubmed
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pubmed-article:10028982pubmed:articleTitleAngiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training.lld:pubmed
pubmed-article:10028982pubmed:affiliationCentre for Cardiovascular Genetics, University College London, Rayne Institute, UK. h.montgomery@ucl.ac.uklld:pubmed
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