| pubmed-article:10024665 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C0002345 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C0679058 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C1547699 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C1519595 | lld:lifeskim |
| pubmed-article:10024665 | lifeskim:mentions | umls-concept:C0048607 | lld:lifeskim |
| pubmed-article:10024665 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10024665 | pubmed:dateCreated | 1999-3-23 | lld:pubmed |
| pubmed-article:10024665 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:abstractText | Glucosidase II is a processing enzyme of the endoplasmic reticulum that functions to hydrolyze two glucose residues in immature N -linked oligosaccharides attached to newly synthesized polypeptides. We previously reported the cDNA cloning of the alpha- and beta-subunits of mouse glucosidase II from T cells following copurification of these proteins with the highly glycosylated transmembrane protein-tyrosine phosphatase CD45. Subsequent examination of additional cDNA clones, coupled with partial genomic DNA sequencing, has revealed that both subunits are encoded by gene products that undergo alternative splicing in T lymphocytes. The catalytic alpha-subunit possesses two variably expressed segments, box Alpha1, consisting of 22 amino acids located proximal to the amino-terminus, and box Alpha2, composed of 9 amino acids situated between the amino-terminus and the putative catalytic site in the central region of the molecule. Box Beta1, a variably expressed 7 amino acid segment in the beta-subunit of glucosidase II, is located immediately downstream of an acidic stretch near the carboxyl-terminus. Screening of reverse transcribed RNA by polymerase chain reaction confirms the variable inclusion of each of these segments in transcripts obtained from a panel of T-lymphocyte cell lines. Thus, distinct isoforms of glucosidase II exist that may perform specialized functions. | lld:pubmed |
| pubmed-article:10024665 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10024665 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10024665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10024665 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10024665 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:10024665 | pubmed:issn | 0959-6658 | lld:pubmed |
| pubmed-article:10024665 | pubmed:author | pubmed-author:OstergaardH... | lld:pubmed |
| pubmed-article:10024665 | pubmed:author | pubmed-author:ArendtC WCW | lld:pubmed |
| pubmed-article:10024665 | pubmed:author | pubmed-author:DawickiWW | lld:pubmed |
| pubmed-article:10024665 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10024665 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:10024665 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10024665 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10024665 | pubmed:pagination | 277-83 | lld:pubmed |
| pubmed-article:10024665 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:meshHeading | pubmed-meshheading:10024665... | lld:pubmed |
| pubmed-article:10024665 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10024665 | pubmed:articleTitle | Alternative splicing of transcripts encoding the alpha- and beta-subunits of mouse glucosidase II in T lymphocytes. | lld:pubmed |
| pubmed-article:10024665 | pubmed:affiliation | Department of Medical Microbiology and Immunology, University of Alberta, Edmonton T6G 2H7, Canada. | lld:pubmed |
| pubmed-article:10024665 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10024665 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10024665 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:14376 | entrezgene:pubmed | pubmed-article:10024665 | lld:entrezgene |
| entrez-gene:19089 | entrezgene:pubmed | pubmed-article:10024665 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10024665 | lld:pubmed |
