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family:comment |
Apc9 is one of the subunits of the anaphase-promoting complex,or cyclosome [1], which is essential for regulating entry into anaphase and exit from mitosis. The APC is a ubiquitin-protein ligase complex. All APC subunits are members of the cullin family proteins, which bind to a ring-finger subunit via a conserved cullin domain [2]. The APC is made up of four parts, the third of which is a tetratricopeptide repeat arm (TPR) that contains Apc9 [3].
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