Source:http://linkedlifedata.com/resource/pfam/family/PF07834.6
| Predicate | Object |
|---|---|
| rdf:type | |
| family:comment |
Ran-GTPase activating protein 1 (RanGAP1, Swiss:P46061) is aGTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Its C-terminal domain is required for RanGAP1 localisation at the vertebrate nuclear pore complex, and is sumoylated by the small ubiquitin-related modifier protein (SUMO-1, Swiss:Q93068). This domain is composed almost entirely of helical substructures that are organised into an alpha-alpha superhelix fold, with the exception of the peptide containing the lysine residue required for SUMO-1 conjugation [1].
|
| family:id |
RanGAP1_C
|
| family:description |
RanGAP1 C-terminal domain
|
| family:authorList |
Fenech M
|
| family:familyType |
Domain
|
| family:dbReference | |
| family:pubmed | |
| family:protein |