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Alpha-A conotoxin PIVA (Swiss:P55963) is the major paralytic toxin found in the venom produced by the piscivorous snail Conus purpurascens. This peptide acts by blocking the acetylcholine binding site of the nicotinic acetylcholine receptor at the neuromuscular junction [1]. The overall shape of the peptide is described as an "iron" with a highly charged hydrophilic loop of 15S-19R forming the "handle" domain that
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Toxin_14
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Alpha-A conotoxin PIVA-like protein
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Fenech M
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Domain
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