Source:http://linkedlifedata.com/resource/pfam/family/PF07213.6
| Predicate | Object |
|---|---|
| rdf:type | |
| family:comment |
This family consists of several mammalian DAP10 membraneproteins. In activated mouse natural killer (NK) cells, the NKG2D receptor associates with two intracellular adaptors, DAP10 and DAP12, which trigger phosphatidyl inositol 3 kinase (PI3K) and Syk family protein tyrosine kinases, respectively. It has been suggested that the DAP10-PI3K pathway is sufficient to initiate NKG2D-mediated killing of target cells [1].
|
| family:id |
DAP10
|
| family:description |
DAP10 membrane protein
|
| family:authorList |
Moxon SJ
|
| family:familyType |
Family
|
| family:dbReference | |
| family:pubmed | |
| family:protein |