Linked Life Data

PF05438.7

Source:http://linkedlifedata.com/resource/pfam/family/PF05438.7

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
family:comment
This family consists of several thyrotropin-releasing hormone(TRH) proteins. Thyrotropin-Releasing Hormone (TRH; pyroGlu-His-Pro-NH2), originally isolated as a hypothalamic neuropeptide hormone, most likely acts also as a neuromodulator and/or neurotransmitter in the central nervous system (CNS). This interpretation is supported by the identification of a peptidase localised on the surface of neuronal cells which has been termed TRH-degrading ectoenzyme (TRH-DE) since it selectively inactivates TRH [1]. TRH has been used clinically for the treatment of spinocerebellar degeneration and disturbance of consciousness in humans [2].
family:id
TRH
family:description
Thyrotropin-releasing hormone (TRH)
family:authorList
Moxon SJ
family:familyType
Family
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family:pubmed
family:wikiPage
family:protein