Major Histocompatibility Complex


MSH: The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) TRANSPLANTATION ANTIGENS, genes which control the structure of the IMMUNE RESPONSE-ASSOCIATED ANTIGENS, HUMAN; the IMMUNE RESPONSE GENES which control the ability of an animal to respond immunologically to antigenic stimuli, and genes which determine the structure and/or level of the first four components of complement.,CSP: genetic region found in all mammals whose products are primarily reponsible for the rapid rejection of grafts between individuals and which signal between lymphocytes and cells expressing antigen; H-2 in mouse and HLA in humans.

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