<http://www.reactome.org/biopax/48887Pathway819> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#Pathway> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#comment> "Edited: Orlic-Milacic, M, 2012-02-10"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Jassal, B, 2004-12-15 13:08:03"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Joutel, A, 2004-12-15"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#comment> "Similar to NOTCH1, NOTCH3 is activated by delta-like and jagged ligands (DLL/JAG) expressed in trans on a neighboring cell. The activation triggers cleavage of NOTCH3, first by ADAM10 at the S2 cleavage site, then by gamma-secretase at the S3 cleavage site, resulting in the release of the intracellular domain of NOTCH3, NICD3, into the cytosol. NICD3 subsequently traffics to the nucleus where it acts as a transcriptional regulator."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:GENE+ONTOLOGY_GO%3A0007219> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_118862_2> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_1980148> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#displayName> "Signaling by NOTCH3"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#organism> <http://identifiers.org/taxonomy/9606> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#pathwayComponent> <http://www.reactome.org/biopax/48887BiochemicalReaction2947> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#pathwayComponent> <http://www.reactome.org/biopax/48887BiochemicalReaction3338> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#pathwayComponent> <http://www.reactome.org/biopax/48887BiochemicalReaction9> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#pathwayComponent> <http://www.reactome.org/biopax/48887BiochemicalReaction3339> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#pathwayOrder> <http://www.reactome.org/biopax/48887PathwayStep4219> .
<http://www.reactome.org/biopax/48887Pathway819> <http://www.biopax.org/release/biopax-level3.owl#pathwayOrder> <http://www.reactome.org/biopax/48887PathwayStep4220> .