<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#BiochemicalReaction> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Akkerman, JW, 2009-09-04"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Harper, MT, 2009-11-02"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Poole, AW, 2009-11-02"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Jones, ML, 2009-11-02"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#comment> "Edited: Jupe, S, 2009-11-03"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#comment> "Vav interacts directly with PIP2 and PIP3, with a fivefold selectivity for PIP3 over PIP2. PIP3 gives a twofold stimulation of Vav1 GEF activity while PIP2 leads to 90% inhibition. Binding probably occurs through the PH domain, known to bind phosphoinositides."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/9438848> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_434633> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_20604_3> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#displayName> "PIP2 inhibits Vav"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule761> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887Protein4370> .
<http://www.reactome.org/biopax/48887BiochemicalReaction927> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887Complex1080> .