Source:http://www.reactome.org/biopax/48887BiochemicalReaction4280
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3-hydroxy-3-methylglutaryl Coenzyme A synthase (HMG-CoA synthase) catalyzes the condensation of acetyl CoA with acetoacetyl CoA to produce HMG-CoA. There are two forms of this enzyme, cytosolic and mitochondrial. The cytosolic form is ubiquitous in the body and is involved in cholesterol biosynthesis and synthesis of other isoprenoid products. The mitochondrial form, found solely in the liver and kidney, is involved in the ketogenic pathway.,
Authored: Jassal, B, 2007-01-24 15:15:12,
Reviewed: D'Eustachio, P, 2007-01-22 01:32:07
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Condensation of acetyl CoA with acetoacetyl CoA to form HMG-CoA
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2.3.3.10
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