Source:http://www.reactome.org/biopax/48887BiochemicalReaction274
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Authored: D'Eustachio, P, 2008-11-29 15:41:00,
Edited: D'Eustachio, P, 2008-11-29 15:41:00,
RARS2 (mitochondrial arginyl tRNA synthetase) catalyzes the reaction of arginine, mitochondrial tRNA(Arg), and ATP to form Arg tRNA(Arg), AMP, and pyrophosphate. The enzyme is a class I tRNA synthetase. Homozygosity for <I>RARS2</I> mutations has been associated with pontocerebellar hypoplasia â?? a disease characterized by a severe reduction in cerebellum and brainstem size (Edvardson et al. 2007).,
Reviewed: Antonellis, A, 2008-12-02 16:58:45
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arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
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6.1.1.19
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