. "Reviewed: Gotoh, N, 2011-08-26"^^ . "Authored: Rothfels, K, 2011-08-15"^^ . "Once recruited to the activated receptor, PI3K phosphorylates PIP2 to PIP3, leading to activation of AKT signaling. PI3K signaling has been demonstrated in ZMYM2-, FOP- and BCR-FGFR1 fusions (Chen, 2004; Demiroglu, 2001; Guasch, 2001), as well as downstream of a number of other FGFR mutants (see for instance, Byron, 2008; Kunii, 2008; Agazie, 2003; Takeda, 2007)."^^ . . . . . . . "FGFR associated PI3K phosphorylates PIP2 to PIP3"^^ . . . . .