. "Reviewed: Zhang, Weizhen, 2009-08-29"^^ . "Authored: May, B, 2009-06-10"^^ . "Edited: May, B, 2009-06-10"^^ . "The majority of circulating ghrelin is not acylated (des-acyl ghrelin). Acyl ghrelin can be deacylated in the bloodstream by butyrylcholinesterase and platelet-activating factor acetylhydrolase, which are associated with circulating lipids. Other enzymes may also have this capability. It is unknown if a portion of des-acyl ghrelin in the bloodstream is generated by direct synthesis and secretion."^^ . . . . . . . . . "Deacylation of Acyl Ghrelin"^^ . "3.1"^^ . . .