. "Edited: May, B, 2011-01-23"^^ . "Reviewed: Peng, C, 2011-08-24"^^ . "Authored: May, B, 2011-01-23"^^ . "As inferred from the response of the activin receptor to activin, the type II component of the NODAL receptor phosphorylates the type I component in response to NODAL binding. Experiments with human proteins in frog oocytes show NODAL can signal via the CRIPTO:ACVR1B(ALK4):ACVR2 complex (Yeo and Whitman 2001)."^^ . . . . . . "Type II Activin Receptor (ActRII/ACVR2) Phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in Response to NODAL"^^ . "2.7.11"^^ . . . . . . .