Source:http://www.reactome.org/biopax/48887BiochemicalReaction1033
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Authored: D'Eustachio, P, 2005-02-14 18:06:15,
Edited: D'Eustachio, P, 0000-00-00 00:00:00,
The uncleaved (one-chain) form of urokinase plasminogen activator associates with urokinase plasminogen activator receptor (uPAR), forming a complex at the cell surface (Cubellis et al. 1986). The complex is anchored to the outer face of the plasma membrane by a glycophosphatidylinositol moiety at the carboxy terminus of uPAR (Behrendt et al. 1990; Ploug et al. 1991).
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urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR
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