@prefix activity: . @prefix address: . @prefix agency: . @prefix assay: . @prefix assayCategory: . @prefix assayTargetLink: . @prefix biopax3: . @prefix calbc: . @prefix calbc-group: . @prefix carrierLink: . @prefix certainAgreement: . @prefix chebi: . @prefix chembl: . @prefix chemicalCompound: . @prefix chemicalCompoundRecord: . @prefix clan: . @prefix clinicalResult: . @prefix clinicalStudy: . @prefix clinicaltrials: . @prefix company: . @prefix confidenceScore: . @prefix contact: . @prefix country: . @prefix cpath: . @prefix curationLookup: . @prefix dailymed: . @prefix dailymed-drugs: . @prefix dailymed-ingredient: . @prefix dailymed-instance: . @prefix databaseReference: . @prefix dc: . @prefix dc-term: . @prefix diseaseontology: . @prefix diseasome: . @prefix diseasome-diseases: . @prefix diseasome-gene: . @prefix diseasome-instance: . @prefix documentType: . @prefix dosageForm: . @prefix drug: . @prefix drugbank: . @prefix drugbank-proteinSequence: . @prefix drugCategory: . @prefix drugInteraction: . @prefix drugTarget: . @prefix eligibility: . @prefix entrez-gene: . @prefix entrez-goterm: . @prefix entrezgene: . @prefix enzymeLink: . @prefix externalIdentifier: . @prefix externalLink: . @prefix factforge: . @prefix family: . @prefix foaf: . @prefix formulation: . @prefix freebase: . @prefix gene-rif: . @prefix geneontology: . @prefix geneSequence: . @prefix hapmap: . @prefix indication: . @prefix intervention: . @prefix investigator: . @prefix label: . @prefix lhgdn: . @prefix lifeskim: . @prefix linkedct: . @prefix linkedct-condition: . @prefix linkedct-intervention: . @prefix literatureCitation: . @prefix lld: . @prefix location: . @prefix measurement: . @prefix meddraSideEffect: . @prefix mixture: . @prefix molecularSpecies: . @prefix molecule: . @prefix moleculeType: . @prefix ontotext: . @prefix organismSpecies: . @prefix outcomeAnalysis: . @prefix outcomeMeasure: . @prefix overallOfficial: . @prefix owl: . @prefix owlim: . @prefix packager: . @prefix participantFlow: . @prefix patent: . @prefix pfam: . @prefix phenotype: . @prefix pointOfContact: . @prefix price: . @prefix primaryOutcome: . @prefix product: . @prefix property: . @prefix proteinSequence: . @prefix pubmed: . @prefix pubmed-article: . @prefix pubmed-author: . @prefix pubmed-mesh: . @prefix pubmed-meshheading: . @prefix pubmed-qualifier: . @prefix rdf: . @prefix rdfs: . @prefix relationshipType: . @prefix relontology: . @prefix reportingGroup: . @prefix researchStem: . @prefix responsibleParty: . @prefix result: . @prefix resultsBaseline: . @prefix resultsMeasure: . @prefix resultsOutcome: . @prefix secondaryOutcome: . @prefix sideEffect: . @prefix sideEffectFrequency: . @prefix sider: . @prefix sider-drug: . @prefix skos: . @prefix skos-xl: . @prefix snp: . @prefix structureType: . @prefix studyMilestone: . @prefix studyParticipants: . @prefix studyPeriod: . @prefix substructure: . @prefix symptom: . @prefix synonym: . @prefix targetLink: . @prefix targetType: . @prefix taxonomy: . @prefix taxonomyClass: . @prefix taxonomyKingdom: . @prefix transporterLink: . @prefix umls: . @prefix umls-concept: . @prefix umls-label: . @prefix umls-semnetwork: . @prefix uniprot: . @prefix uniprot-protein: . @prefix uniprot-unstable: . @prefix xsd: . a owl:Class , owl:Class , owl:Class ; rdfs:comment """Definition: A conversion interaction in which one or more entities (substrates) undergo covalent changes to become one or more other entities (products). The substrates of biochemical reactions are defined in terms of sums of species. This is convention in biochemistry, and, in principle, all of the EC reactions should be biochemical reactions. Examples: ATP + H2O = ADP + Pi Comment: In the example reaction above, ATP is considered to be an equilibrium mixture of several species, namely ATP4-, HATP3-, H2ATP2-, MgATP2-, MgHATP-, and Mg2ATP. Additional species may also need to be considered if other ions (e.g. Ca2+) that bind ATP are present. Similar considerations apply to ADP and to inorganic phosphate (Pi). When writing biochemical reactions, it is not necessary to attach charges to the biochemical reactants or to include ions such as H+ and Mg2+ in the equation. The reaction is written in the direction specified by the EC nomenclature system, if applicable, regardless of the physiological direction(s) in which the reaction proceeds. Polymerization reactions involving large polymers whose structure is not explicitly captured should generally be represented as unbalanced reactions in which the monomer is consumed but the polymer remains unchanged, e.g. glycogen + glucose = glycogen."""^^xsd:string , """Definition: A conversion interaction in which one or more entities (substrates) undergo covalent changes to become one or more other entities (products). The substrates of biochemical reactions are defined in terms of sums of species. This is convention in biochemistry, and, in principle, all of the EC reactions should be biochemical reactions. Examples: ATP + H2O = ADP + Pi Comment: In the example reaction above, ATP is considered to be an equilibrium mixture of several species, namely ATP4-, HATP3-, H2ATP2-, MgATP2-, MgHATP-, and Mg2ATP. Additional species may also need to be considered if other ions (e.g. Ca2+) that bind ATP are present. Similar considerations apply to ADP and to inorganic phosphate (Pi). When writing biochemical reactions, it is not necessary to attach charges to the biochemical reactants or to include ions such as H+ and Mg2+ in the equation. The reaction is written in the direction specified by the EC nomenclature system, if applicable, regardless of the physiological direction(s) in which the reaction proceeds. Polymerization reactions involving large polymers whose structure is not explicitly captured should generally be represented as unbalanced reactions in which the monomer is consumed but the polymer remains unchanged, e.g. glycogen + glucose = glycogen."""^^xsd:string , """Definition: A conversion interaction in which one or more entities (substrates) undergo covalent changes to become one or more other entities (products). The substrates of biochemical reactions are defined in terms of sums of species. This is convention in biochemistry, and, in principle, all of the EC reactions should be biochemical reactions. Examples: ATP + H2O = ADP + Pi Comment: In the example reaction above, ATP is considered to be an equilibrium mixture of several species, namely ATP4-, HATP3-, H2ATP2-, MgATP2-, MgHATP-, and Mg2ATP. Additional species may also need to be considered if other ions (e.g. Ca2+) that bind ATP are present. Similar considerations apply to ADP and to inorganic phosphate (Pi). When writing biochemical reactions, it is not necessary to attach charges to the biochemical reactants or to include ions such as H+ and Mg2+ in the equation. The reaction is written in the direction specified by the EC nomenclature system, if applicable, regardless of the physiological direction(s) in which the reaction proceeds. Polymerization reactions involving large polymers whose structure is not explicitly captured should generally be represented as unbalanced reactions in which the monomer is consumed but the polymer remains unchanged, e.g. glycogen + glucose = glycogen."""^^xsd:string ; owl:disjointWith , , ; rdfs:subClassOf , , .