Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements.
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| rdfs:subClassOf | |
| rdfs:label |
estrogen nuclear receptor activity,
estrogen-activated RNA polymerase II transcription factor binding transcription factor activity
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| skos:exactMatch |