. . . . . . "NCI: Human MAPK8 wild-type allele is located in the vicinity of 10q11.22 and is approximately 133 kb in length. This allele, which encodes mitogen-activated protein kinase 8 protein, plays a role in the induction of programmed cell death mediated by both tumor necrosis factor-alpha and ultraviolet radiation." . . . . . . . . . . . .