Source:http://linkedlifedata.com/resource/geneontology/id/GO:0070375
Predicate | Object |
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rdf:type | |
skos:definition |
"An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:add, GOC:signaling, ISBN:0896039986, PMID:16376520, PMID:16880823, PMID:20811974]
|
skos:inScheme | |
skos:prefLabel |
ERK5 cascade
|
skos:altLabel |
BMK cascade,
BMK signaling pathway,
BMK signalling pathway,
BMK1 cascade,
ERK5 signaling pathway,
MAPK7 cascade,
big MAP kinase signaling cascade,
extracellular signal-regulated kinase 5 cascade
|
skos:broader |