. "\"A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.\" [GOC:mah, GOC:signaling]" . . "transmembrane receptor protein serine/threonine kinase signaling pathway" . "transmembrane receptor protein serine/threonine kinase signalling pathway" . .