Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004221
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: ubiquitin C-terminal thiolester + H2O = ubiquitin + a thiol. Hydrolysis of esters, including those formed between thiols such as dithiothreitol or glutathione and the C-terminal glycine residue of the polypeptide ubiquitin, and AMP-ubiquitin." [EC:3.1.2.15]
|
| skos:inScheme | |
| skos:prefLabel |
ubiquitin thiolesterase activity
|
| skos:altLabel |
ubiquitin carboxy-terminal esterase activity,
ubiquitin thioesterase activity,
ubiquitin-C-terminal-thioester hydrolase activity
|
| skos:notation |
EC:3.1.2.15,
MetaCyc:UBIQUITIN-THIOLESTERASE-RXN
|
| skos:note |
Note that this term is distinguished from 'ubiquitin-specific protease activity ; GO:0004843' in that it specifically refers to hydrolysis of thiolester bonds, but encompasses the removal of any substrate attached to ubiquitin via a thiolester bond.
|
| skos:broader | |
| skos:relatedSynonym |
ubiquitin C-terminal hydrolase activity,
ubiquitin carboxy-terminal hydrolase activity
|
| skos:narrowSynonym |
ubiquitinyl hydrolase 1 activity
|