Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155807-1111
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
ATR-induced phosphorylation of Chk1-Ser(345) requires PP2A only when Vpr activates ATR,
HIV-1 Vpr activates ATR, resulting in phosphorylation of Chk1 and activation of the ATR-mediated DNA damage response,
Phosphorylation of Chk1 at position Ser345 is required for HIV-1 Vpr-induced G2/M arrest, possibly through signaling of DNA re-replication via Cdt1
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| entrezgene:keyphrase |
induces phosphorylation of,
activates
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