Predicate | Object |
---|---|
rdf:type | |
biopax3:comment |
FUNCTION: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. SUBUNIT: Found in a complex with VAMP8 and STX7 in the liver. Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, STX8 and VAMP8 (By similarity). SUBCELLULAR LOCATION: Endomembrane system; Single-pass type IV membrane protein. Cytoplasmic granule. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=Long; IsoId=Q9UEU0-1; Sequence=Displayed; Name=Short; IsoId=Q9UEU0-2; Sequence=VSP_006753; TISSUE SPECIFICITY: Expressed in all tissues examined. SIMILARITY: Belongs to the VTI1 family. GENE SYNONYMS:VTI1B VTI1 VTI1L VTI1L1 VTI2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 232 AA; 26688 MW; B421C2863235B9B1 CRC64;
|
biopax3:xref | |
biopax3:displayName |
VTI1B_HUMAN
|
biopax3:name |
VTI1B,
Vesicle transport v-SNARE protein Vti1-like 1,
Vti1-rp1
|
biopax3:entityFeature | |
biopax3:organism | |
biopax3:sequence |
MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGLVYYKFFRSH
|
biopax3:standardName |
Vesicle transport through interaction with t-SNAREs homolog 1B
|