| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
SEQUENCE 632 AA; 68222 MW; 13940F2FBD6215D0 CRC64;,
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus (Probable). Note=Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H201-1; Sequence=Displayed; Name=2; IsoId=Q9H201-2; Sequence=VSP_009158, VSP_009159; Note=No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay; TISSUE SPECIFICITY: Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis. INDUCTION: In keratinocytes, by wounding or contact with collagen. SIMILARITY: Belongs to the epsin family. SIMILARITY: Contains 1 ENTH (epsin N-terminal homology) domain. SIMILARITY: Contains 2 UIM (ubiquitin-interacting motif) repeats. GENE SYNONYMS:EPN3. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:18235,
urn:biopax:RelationshipXref:NCBI GENE_55040,
urn:biopax:RelationshipXref:REFSEQ_NP_060427,
urn:biopax:UnificationXref:UNIPROT_A8K6J3,
urn:biopax:UnificationXref:UNIPROT_A8KAB2,
urn:biopax:UnificationXref:UNIPROT_Q9BVN6,
urn:biopax:UnificationXref:UNIPROT_Q9H201,
urn:biopax:UnificationXref:UNIPROT_Q9NWK2
|
| biopax3:displayName |
EPN3_HUMAN
|
| biopax3:name |
EPN3,
EPS-15-interacting protein 3
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL
|
| biopax3:standardName |
Epsin-3
|