Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Has a beta-galactosyltransferase activity; transfers beta-galactose to hydroxylysine residues on collagen. CATALYTIC ACTIVITY: UDP-galactose + 5-hydroxy-L-lysine- [procollagen] = UDP + 5-(D-galactosyloxy)-L-lysine-[procollagen]. BIOPHYSICOCHEMICAL PROPERTIES: Kinetic parameters: KM=33.5 uM for UDP-galactose; SUBCELLULAR LOCATION: Endoplasmic reticulum lumen (Potential). TISSUE SPECIFICITY: Expressed in brain and skeletal muscle. SIMILARITY: Belongs to the glycosyltransferase 25 family. CAUTION: Has no glucosyltransferase activity. SEQUENCE CAUTION: Sequence=BAA25510.1; Type=Erroneous initiation; GENE SYNONYMS:GLT25D2 C1orf17 KIAA0584. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 626 AA; 72924 MW; 697A76DB73F67539 CRC64;
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biopax3:xref | |
biopax3:displayName |
GT252_HUMAN
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biopax3:name |
2.4.1.50,
GLT25D2,
Glycosyltransferase 25 family member 2,
Hydroxylysine galactosyltransferase 2
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biopax3:organism | |
biopax3:sequence |
MAARPAATLAWSLLLLSSALLREGCRARFVAERDSEDDGEEPVVFPESPLQSPTVLVAVLARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEIFREWLKNVQRLYHYVEWRPMDEPESYPDEIGPKHWPTSRFAHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNLLIAENKTIVAPMLESRGLYSNFWCGITPKGFYKRTPDYVQIREWKRTGCFPVPMVHSTFLIDLRKEASDKLTFYPPHQDYTWTFDDIIVFAFSSRQAGIQMYLCNREHYGYLPIPLKPHQTLQEDIENLIHVQIEAMIDRPPMEPSQYVSVVPKYPDKMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLKALNIEMLPGYRDPYSSRPLTRGEIGCFLSHYSVWKEVIDRELEKTLVIEDDVRFEHQFKKKLMKLMDNIDQAQLDWELIYIGRKRMQVKEPEKAVPNVANLVEADYSYWTLGYVISLEGAQKLVGANPFGKMLPVDEFLPVMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETSTIWDNETVATDWDRTHAWKSRKQSRIYSNAKNTEALPPPTSLDTVPSRDEL
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biopax3:standardName |
Procollagen galactosyltransferase 2
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