| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye. DEVELOPMENTAL STAGE: Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth. SIMILARITY: Belongs to the POU transcription factor family. Class- 4 subfamily. SIMILARITY: Contains 1 homeobox DNA-binding domain. SIMILARITY: Contains 1 POU-specific domain. SEQUENCE CAUTION: Sequence=CAA45907.1; Type=Frameshift; Positions=11, 13, 33, 43, 57, 61, 74, 76, 133, 135, 138, 340, 342; WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/POU4F1ID44173ch13q31.html"; GENE SYNONYMS:POU4F1 BRN3A RDC1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 419 AA; 42697 MW; 6EDC2A2082F95F23 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:9218,
urn:biopax:RelationshipXref:NCBI GENE_5457,
urn:biopax:RelationshipXref:REFSEQ_NP_006228,
urn:biopax:UnificationXref:UNIPROT_Q01851,
urn:biopax:UnificationXref:UNIPROT_Q14986,
urn:biopax:UnificationXref:UNIPROT_Q15318,
urn:biopax:UnificationXref:UNIPROT_Q5T227
|
| biopax3:displayName |
PO4F1_HUMAN
|
| biopax3:name |
Brain-3A,
Brain-specific homeobox/POU domain protein 3A,
Brn-3A,
Homeobox/POU domain protein RDC-1,
Oct-T1,
POU4F1
|
| biopax3:organism | |
| biopax3:sequence |
MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY
|
| biopax3:standardName |
POU domain, class 4, transcription factor 1
|