| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. FUNCTION: Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity). SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. TISSUE SPECIFICITY: Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. INDUCTION: By alpha interferons. Decreased levels in THP-1 cells after treatment with recombinant interferon-lambda. SIMILARITY: Belongs to the thymosin beta family. GENE SYNONYMS:TMSB4X TB4X THYB4 TMSB4. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 44 AA; 5053 MW; 440C6158482DAAD0 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:11881,
urn:biopax:RelationshipXref:NCBI GENE_7114,
urn:biopax:RelationshipXref:REFSEQ_NP_066932,
urn:biopax:UnificationXref:UNIPROT_P01253,
urn:biopax:UnificationXref:UNIPROT_P01254,
urn:biopax:UnificationXref:UNIPROT_P62328,
urn:biopax:UnificationXref:UNIPROT_Q546P5,
urn:biopax:UnificationXref:UNIPROT_Q63576,
urn:biopax:UnificationXref:UNIPROT_Q9UE55
|
| biopax3:displayName |
TYB4_HUMAN
|
| biopax3:name |
Fx,
Hematopoietic system regulatory peptide,
Seraspenide,
T beta-4,
TMSB4X
|
| biopax3:entityFeature |
urn:biopax:ModificationFeature:TYB4_HUMAN_1,
urn:biopax:ModificationFeature:TYB4_HUMAN_2,
urn:biopax:ModificationFeature:TYB4_HUMAN_3,
urn:biopax:ModificationFeature:TYB4_HUMAN_4,
urn:biopax:ModificationFeature:TYB4_HUMAN_5,
urn:biopax:ModificationFeature:TYB4_HUMAN_6,
urn:biopax:ModificationFeature:TYB4_HUMAN_7
|
| biopax3:organism | |
| biopax3:sequence |
MSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
|
| biopax3:standardName |
Thymosin beta-4
|