| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Localized exclusively in the central nervous system, predominantly in the corpus striatum but also in various limbic and cortical regions. SIMILARITY: Belongs to the G-protein coupled receptor 1 family. GENE SYNONYMS:Htr6. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 436 AA; 46923 MW; 6BC00F6A3CBA5FB4 CRC64;
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| biopax3:xref | |
| biopax3:displayName |
5HT6R_RAT
|
| biopax3:name |
5-HT-6,
5-HT6,
Htr6,
ST-B17,
Serotonin receptor 6
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIVLICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTPAPGQCRLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTAGQALETLQVPRTPRPGMESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVPDQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLSQTLWSLRYGRIHSVPP
|
| biopax3:standardName |
5-hydroxytryptamine receptor 6
|