| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. SUBUNIT: The C-terminus interacts with SHANK1 PDZ domain (By similarity). SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=A; Synonyms=SS2RA; IsoId=P30875-1; Sequence=Displayed; Name=B; Synonyms=SS2RB; IsoId=P30875-2; Sequence=VSP_001923; TISSUE SPECIFICITY: Cerebrum and kidney. SIMILARITY: Belongs to the G-protein coupled receptor 1 family. GENE SYNONYMS:Sstr2 Smstr2 Sst2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 369 AA; 41222 MW; A78845AF74823039 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:98328,
urn:biopax:RelationshipXref:NCBI GENE_20606,
urn:biopax:RelationshipXref:REFSEQ_NP_001036071,
urn:biopax:RelationshipXref:REFSEQ_NP_033243,
urn:biopax:UnificationXref:UNIPROT_P30875,
urn:biopax:UnificationXref:UNIPROT_P30934,
urn:biopax:UnificationXref:UNIPROT_Q91Y73
|
| biopax3:displayName |
SSR2_MOUSE
|
| biopax3:name |
SRIF-1,
SS-2-R,
SS2-R,
SS2R,
Sstr2
|
| biopax3:organism | |
| biopax3:sequence |
MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
|
| biopax3:standardName |
Somatostatin receptor type 2
|