| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. SUBUNIT: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5 AND CCT8. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. SIMILARITY: Belongs to the TCP-1 chaperonin family. GENE SYNONYMS:TCP1 CCT1 CCTA. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 556 AA; 60344 MW; 486ECA836EA258A1 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:11655,
urn:biopax:RelationshipXref:NCBI GENE_6950,
urn:biopax:RelationshipXref:REFSEQ_NP_110379,
urn:biopax:UnificationXref:UNIPROT_E1P5B2,
urn:biopax:UnificationXref:UNIPROT_P17987,
urn:biopax:UnificationXref:UNIPROT_Q15556,
urn:biopax:UnificationXref:UNIPROT_Q5TCM3
|
| biopax3:displayName |
TCPA_HUMAN
|
| biopax3:name |
CCT-alpha,
TCP-1-alpha,
TCP1
|
| biopax3:entityFeature |
urn:biopax:ModificationFeature:TCPA_HUMAN_1,
urn:biopax:ModificationFeature:TCPA_HUMAN_2,
urn:biopax:ModificationFeature:TCPA_HUMAN_3,
urn:biopax:ModificationFeature:TCPA_HUMAN_4,
urn:biopax:ModificationFeature:TCPA_HUMAN_5,
urn:biopax:ModificationFeature:TCPA_HUMAN_6,
urn:biopax:ModificationFeature:TCPA_HUMAN_7
|
| biopax3:organism | |
| biopax3:sequence |
MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGALND
|
| biopax3:standardName |
T-complex protein 1 subunit alpha
|