| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. SUBUNIT: Interacts with MPDZ. Interacts with ARRB2 (By similarity). SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. DOMAIN: The PDZ domain-binding motif is involved in the interaction with MPDZ. PTM: N-glycosylated (By similarity). SIMILARITY: Belongs to the G-protein coupled receptor 1 family. GENE SYNONYMS:Htr2c 5ht1c Htr1c. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 460 AA; 51917 MW; D44E977D8F80047E CRC64;
|
| biopax3:xref | |
| biopax3:displayName |
5HT2C_RAT
|
| biopax3:name |
5-HT-1C,
5-HT-2C,
5-HT1C,
5-HT2C,
5-HTR2C,
5-hydroxytryptamine receptor 1C,
Htr2c,
Serotonin receptor 2C
|
| biopax3:organism | |
| biopax3:sequence |
MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
|
| biopax3:standardName |
5-hydroxytryptamine receptor 2C
|