| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. SUBUNIT: C8 is composed of three chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. SUBCELLULAR LOCATION: Secreted. SIMILARITY: Belongs to the calycin superfamily. Lipocalin family. GENE SYNONYMS:C8G. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 202 AA; 22277 MW; 4E4F73140E607FFE CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:1354,
urn:biopax:RelationshipXref:NCBI GENE_733,
urn:biopax:RelationshipXref:REFSEQ_NP_000597,
urn:biopax:UnificationXref:UNIPROT_P07360,
urn:biopax:UnificationXref:UNIPROT_Q14CT8,
urn:biopax:UnificationXref:UNIPROT_Q14CU0,
urn:biopax:UnificationXref:UNIPROT_Q5SQ07
|
| biopax3:displayName |
CO8G_HUMAN
|
| biopax3:name |
C8G
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MLPPGTATLLTLLLAAGSLGQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARDARGAVHVVVAETDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFCEAADQFHVLDEVRR
|
| biopax3:standardName |
Complement component C8 gamma chain
|