Source:http://biocyc.org/biopax/biopax-level3Catalysis149810
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:controlType |
ACTIVATION
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| biopax3:controlled | |
| biopax3:comment |
Calcium-dependent cytosolic phospholipase a2; may serve to translocate Ca2+ to membrane vesicles; contains a Ca2+-dependent phospholipid-binding motif. Summary: Cytosolic phospholipase A2 (PLA2; EC 3.1.1.4) catalyzes the release of arachidonic acid from membrane phospholipids. Arachidonic acid in turn serves as precursor for a wide spectrum of biologic effectors, collectively known as eicosanoids, that are involved in hemodynamic regulation, inflammatory responses, and other cellular processes. Dennis (1994) [PubMed 8175726] reviewed various types of PLA2. The best characterized is the group II PLA2 originally isolated from human synovial fluid (i.e., PLA2G2A; MIM 172411). Groups I (human pancreatic, PLA2G1B (MIM 172410); also found in cobras and kraits), II (synovial; also found in rattlesnakes and vipers), and III (forms of which were described in bee and lizard) are secreted; group IV is cytosolic.[supplied by OMIM] |CITS:[11125071]|
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| biopax3:xref | |
| biopax3:controller | |
| biopax3:dataSource | |
| biopax3:displayName |
Lysophospholipase
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| biopax3:standardName |
Lysophospholipase
|