Source:HTTP://PATHWAYCOMMONS.ORG/PSI2BP#_8855006218586852310
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2011 publication year MI:0886,
A directed protein interaction network for investigating intracellular signal transduction.,
Sci Signal journal MI:0885,
The authors generated a large dataset of interactions using automated yeast two-hybrid interaction mating. Using a set of ~450 signaling related proteins as baits, they identified ~2500 PPIs through repeated Y2H interaction screens. The resulting PPI network connected 1126 proteins through 2626 PPI. comment MI:0612,
Vinayagam A., Stelzl U., Foulle R., Plassmann S., Zenkner M., Timm J., Assmus HE., Andrade-Navarro MA., Wanker EE. author-list MI:0636
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