Interacts with PDZK1IP1 and ABCC2. Binds to the C-terminal region of SLC26A3 (By similarity). Interacts via its PDZ1 domain with the C-terminal domain of SCARB1 and SLCO1A1. Forms a heterodimeric complex with SLC9A3R1. Interacts with AKAP2, BCR, CFTR SLC22A12, SLC22A4, SLC22A5 SLC26A6, SLC9A3R2 and SLC17A1 (By similarity).