biopax-level3Catalysis150338

Source:http://biocyc.org/biopax/biopax-level3Catalysis150338

Statements in which the resource exists.
SubjectPredicateObjectContext
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http://biocyc.org/biopax/bi...biopax3:commentThe kinetic constants are for the enzyme purified directly from human brain. Sulfation proceeds in an ordered, bisubstrate reaction mechanism with PAPS as the leading substrate |CITS: [3860259]|. The enzyme has been reported to undergo substrate inhibition by dopamine |CITS: [14871892]|. The enzyme also has a unique D-dopa/D-tyrosine-sulfating activity stimulated by Mn<sup>2+</sup> |CITS: [12424257]|.lld:biopax3
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