http://linkedlifedata.com/resource/umls/id/C0597357
type: T116
type: T192
type: Concept
has correlation: ANAT
has correlation: GENE
has correlation: PHYS
has correlation: PHEN
has correlation: OBJC
has correlation: CONC
has correlation: CHEM
definition: NCI: A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell.,CSP: diverse family of binding proteins which mediate the biological effects of regulatory molecules such as hormones; many are intrinsic membrane proteins; others (such as the steroid receptors) are cytoplasmic carriers; postcoordinate this term with specific ligand terms.,NCI: A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.
in scheme: umls
broader: http://linkedlifedata.com/resource/umls/id/C0033684
broader: http://linkedlifedata.com/resource/umls/id/C0242210
broader: http://linkedlifedata.com/resource/umls/id/C0815043
narrower: http://linkedlifedata.com/resource/umls/id/C0034828
narrower: http://linkedlifedata.com/resource/umls/id/C0019929
narrower: http://linkedlifedata.com/resource/umls/id/C0034800
narrower: http://linkedlifedata.com/resource/umls/id/C0034805
narrower: http://linkedlifedata.com/resource/umls/id/C0682972
narrower: http://linkedlifedata.com/resource/umls/id/C0206587
narrower: http://linkedlifedata.com/resource/umls/id/C0034799
narrower: http://linkedlifedata.com/resource/umls/id/C0034801
narrower: http://linkedlifedata.com/resource/umls/id/C0034817
narrower: http://linkedlifedata.com/resource/umls/id/C0034822
narrower: http://linkedlifedata.com/resource/umls/id/C0206476
narrower: http://linkedlifedata.com/resource/umls/id/C0682971
narrower: http://linkedlifedata.com/resource/umls/id/C0596248
narrower: http://linkedlifedata.com/resource/umls/id/C0597673
narrower: http://linkedlifedata.com/resource/umls/id/C0205923
narrower: http://linkedlifedata.com/resource/umls/id/C0682769
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