http://linkedlifedata.com/resource/umls/id/C0021027
type: T116
type: T121
type: T129
type: Concept
has correlation: ANAT
has correlation: DISO
has correlation: GENE
has correlation: PHYS
has correlation: PHEN
has correlation: PROC
has correlation: CONC
has correlation: CHEM
definition: MSH: Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.,CSP: glycoproteins found in the blood that function as antibodies; the basic structure is a y shaped molecule consisting of two light polypeptide chains and two heavy polypeptide chains linked by disulfide bonds.,NCI: A protein that acts as an antibody. Immunoglobulins are made by B cells and plasma cells. An Ig is a type of glycoprotein with two heavy chains and two l
in scheme: umls
broader: http://linkedlifedata.com/resource/umls/id/C0017007
broader: http://linkedlifedata.com/resource/umls/id/C0033684
broader: http://linkedlifedata.com/resource/umls/id/C1510464
broader: http://linkedlifedata.com/resource/umls/id/C0003241
broader: http://linkedlifedata.com/resource/umls/id/C0021054
broader: http://linkedlifedata.com/resource/umls/id/C0021072
broader: http://linkedlifedata.com/resource/umls/id/C0036800
narrower: http://linkedlifedata.com/resource/umls/id/C0057002
narrower: http://linkedlifedata.com/resource/umls/id/C0020846
narrower: http://linkedlifedata.com/resource/umls/id/C0020835
narrower: http://linkedlifedata.com/resource/umls/id/C0020843
narrower: http://linkedlifedata.com/resource/umls/id/C0020852
narrower: http://linkedlifedata.com/resource/umls/id/C0020861
narrower: http://linkedlifedata.com/resource/umls/id/C0021013
narrower: http://linkedlifedata.com/resource/umls/id/C0021017
narrower: http://linkedlifedata.com/resource/umls/id/C0055781
narrower: http://linkedlifedata.com/resource/umls/id/C0062525
narrower: http://linkedlifedata.com/resource/umls/id/C0087152
narrower: http://linkedlifedata.com/resource/umls/id/C0063352
narrower: http://linkedlifedata.com/resource/umls/id/C0051268
narrower: http://linkedlifedata.com/resource/umls/id/C0296277
narrower: http://linkedlifedata.com/resource/umls/id/C1309286
narrower: http://linkedlifedata.com/resource/umls/id/C1309287
narrower: http://linkedlifedata.com/resource/umls/id/C1431305
narrower: http://linkedlifedata.com/resource/umls/id/C1308797
narrower: http://linkedlifedata.com/resource/umls/id/C1309370
narrower: http://linkedlifedata.com/resource/umls/id/C0759458
narrower: http://linkedlifedata.com/resource/umls/id/C1308272
narrower: http://linkedlifedata.com/resource/umls/id/C1138490
narrower: http://linkedlifedata.com/resource/umls/id/C1431315
narrower: http://linkedlifedata.com/resource/umls/id/C1310536
narrower: http://linkedlifedata.com/resource/umls/id/C1435271
narrower: http://linkedlifedata.com/resource/umls/id/C1448125
narrower: http://linkedlifedata.com/resource/umls/id/C1312366
narrower: http://linkedlifedata.com/resource/umls/id/C1435868
narrower: http://linkedlifedata.com/resource/umls/id/C1452367
narrower: http://linkedlifedata.com/resource/umls/id/C1448126
narrower: http://linkedlifedata.com/resource/umls/id/C1310480
narrower: http://linkedlifedata.com/resource/umls/id/C0030490
narrower: http://linkedlifedata.com/resource/umls/id/C0724402
narrower: http://linkedlifedata.com/resource/umls/id/C0591747
narrower: http://linkedlifedata.com/resource/umls/id/C0216388
narrower: http://linkedlifedata.com/resource/umls/id/C1309542
narrower: http://linkedlifedata.com/resource/umls/id/C1450357
narrower: http://linkedlifedata.com/resource/umls/id/C1143275
narrower: http://linkedlifedata.com/resource/umls/id/C2352244
narrower: http://linkedlifedata.com/resource/umls/id/C1448192
narrower: http://linkedlifedata.com/resource/umls/id/C1309820
narrower: http://linkedlifedata.com/resource/umls/id/C0722468
narrower: http://linkedlifedata.com/resource/umls/id/C0052097
narrower: http://linkedlifedata.com/resource/umls/id/C0063354
narrower: http://linkedlifedata.com/resource/umls/id/C0063355
narrower: http://linkedlifedata.com/resource/umls/id/C0063416
narrower: http://linkedlifedata.com/resource/umls/id/C0065450
narrower: http://linkedlifedata.com/resource/umls/id/C0069293
narrower: http://linkedlifedata.com/resource/umls/id/C0074681
narrower: http://linkedlifedata.com/resource/umls/id/C0078156
narrower: http://linkedlifedata.com/resource/umls/id/C0082849
narrower: http://linkedlifedata.com/resource/umls/id/C0084735
narrower: http://linkedlifedata.com/resource/umls/id/C0086952
narrower: http://linkedlifedata.com/resource/umls/id/C0103635
narrower: http://linkedlifedata.com/resource/umls/id/C0106933
narrower: http://linkedlifedata.com/resource/umls/id/C0162507
narrower: http://linkedlifedata.com/resource/umls/id/C0168434
narrower: http://linkedlifedata.com/resource/umls/id/C0256541
narrower: http://linkedlifedata.com/resource/umls/id/C0291452