<http://www.reactome.org/biopax/48892Evidence4392> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#Evidence> .
<http://www.reactome.org/biopax/48892Evidence4392> <http://www.biopax.org/release/biopax-level3.owl#comment> "Cholesterol, NADPH + H+, and O2 react to form 24-hydroxycholesterol , NADP+, and H2O. This reaction is catalyzed by CYP46A1 in the endoplasmic reticulum membrane. In the body, this enzyme is expressed predominantly in the brain and is thought to play a major role in cholesterol turnover there (Javitt 2002)."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48892Evidence4392> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/11969205> .
<http://www.reactome.org/biopax/48892Evidence4392> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/10377398> .
<http://www.reactome.org/biopax/48892Evidence4392> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/14640697> .
<http://www.reactome.org/biopax/48892Evidence4392> <http://www.biopax.org/release/biopax-level3.owl#evidenceCode> <http://www.reactome.org/biopax/48892EvidenceCodeVocabulary1> .