<http://www.reactome.org/biopax/48892Evidence4365> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#Evidence> .
<http://www.reactome.org/biopax/48892Evidence4365> <http://www.biopax.org/release/biopax-level3.owl#comment> "5Beta-cholesten-7alpha,12alpha-diol-3-one and NADPH + H+ form 5beta-cholestan-3alpha,7alpha,12alpha-triol and NAPDP+. The reaction is catalyzed by 3alpha-hydroxysteroid dehydrogenase (AKR1C4), a cytosolic enzyme belonging to the aldo-keto reductase family (Dufort et al. 2001). Biochemical studies with rat proteins raise the possibility that other related enzymes may also carry out this reaction in vivo (Russell 2003)."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48892Evidence4365> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/12543708> .
<http://www.reactome.org/biopax/48892Evidence4365> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/11158055> .
<http://www.reactome.org/biopax/48892Evidence4365> <http://www.biopax.org/release/biopax-level3.owl#evidenceCode> <http://www.reactome.org/biopax/48892EvidenceCodeVocabulary1> .