<http://www.reactome.org/biopax/48887Pathway25> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#Pathway> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Huang, Tao, 2012-05-14"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Orlic-Milacic, M, 2012-04-04"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#comment> "Edited: Jassal, B, 2012-04-10"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#comment> "In the nucleus, SMAD2/3:SMAD4 heterotrimer complex acts as a transcriptional regulator. The activity of SMAD2/3 complex is regulated both positively and negatively by association with other transcription factors (Chen et al. 2002, Varelas et al. 2008, Stroschein et al. 1999, Wotton et al. 1999) . In addition, the activity of SMAD2/3:SMAD4 complex can be inhibited by nuclear protein phosphatases and ubiquitin ligases (Lin et al. 2006, Dupont et al. 2009)."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/10531062> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/16751101> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/18568018> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/12150994> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/10199400> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:GENE+ONTOLOGY_GO%3A0006351> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_121061_1> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/19135894> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_2173793> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#displayName> "Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#organism> <http://identifiers.org/taxonomy/9606> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#pathwayComponent> <http://www.reactome.org/biopax/48887Pathway27> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#pathwayComponent> <http://www.reactome.org/biopax/48887Pathway26> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#pathwayOrder> <http://www.reactome.org/biopax/48887PathwayStep122> .
<http://www.reactome.org/biopax/48887Pathway25> <http://www.biopax.org/release/biopax-level3.owl#pathwayOrder> <http://www.reactome.org/biopax/48887PathwayStep100> .