. "Reviewed: Chang, E, 2008-05-21 00:05:41"^^ . "Edited: Matthews, L, 2008-02-03 20:50:13"^^ . "Authored: Jakobi, R, 2008-02-05 11:04:14"^^ . "The subcellular localization of PAK-2 is controlled by nuclear localization and nuclear export signal motifs (Jakobi et al.,2003). The regulatory domain contains a nuclear export signal motif that prevents the nuclear accumulation of full-length PAK-2. The activating proteolytic cleavage disrupts the nuclear export signal in PAK-2 and removes most its regulatory domain. The resulting activated PAK-2p34 fragment contains a nuclear localization signal and translocates to and is retained in the nucleus (Jakobi et al.,2003)."^^ . "Edited: Matthews, L, 2008-05-18 16:50:19"^^ . . . . . . "Proteolytic PAK-2p34 fragment translocates to the nucleus"^^ . . .