. "Edited: D'Eustachio, P, 2006-03-11 18:40:17"^^ . "PAP is generated as a byproduct of sulfonation reactions in vivo; its hydrolysis to AMP and orthophosphate returns its constituents to the pool of molecules available for cytosolic nucleotide metabolism. Bisphosphate 3'-nucleotidase 1catalyzes this reaction efficiently in vitro; whether other nucleotidases also play a role in PAP breakdown in vivo is unknown."^^ . . . . . . . "Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate"^^ . "3.1.3.7"^^ . . . . .