. "Reviewed: D'Eustachio, P, 2008-05-28 08:30:54"^^ . "Edited: Jassal, B, 2008-05-19 12:57:01"^^ . "Authored: Jassal, B, 2008-05-19 12:57:01"^^ . "Cyclophosphamide (CPA) is an alkylating agent used in cancer chemotherapy and an immunosuppressant. CYP2B6 converts CPA to the active metabolite 4-hydroxy-CPA."^^ . . . . . . "Cyclophosphamide is 4-hydroxylated by CYP2B6"^^ . . . . . . . .