. "Cytosolic glutamine synthetase (glutamate-ammonia ligase - GLUL) catalyzes the reaction of glutamate, ammonia, and ATP to form glutamine, ADP, and orthophosphate. The enzyme is a decamer (Krajewski et al. 2008). Mutations in the gene encoding GLUL cause glutamine deficiency in vivo (Haberle et al. 2005)."^^ . . . . . . . "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]"^^ . "6.3.1.2"^^ . "mate-ammonia"^^ . . . . . . .