<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#BiochemicalReaction> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: D'Eustachio, P, 2011-08-23"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#comment> "Edited: Jassal, B, 2011-08-17"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Jassal, B, 2011-08-17"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#comment> "The first and rate-limiting enzyme in tetrahydrobiopterin de novo biosynthesis is GTP cyclohydrolase I (GCH1, GTPCHI). Three different isoforms are produced but only isoform 1 is functionally active (G\u00FCtlich et al. 1994). GCH1 is functional as a homodecamer. First, a monomer of GCH1 forms a dimer. Then five dimers arrange into a ring-like structure to form the homodecamer (Nar et al. 1995)."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/7663943> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/8068008> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_111143_1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_1474146> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#displayName> "GCH1 reduces GTP to dihydroneopterin triphosphate"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#eCNumber> "3.5.4.16"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule11> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule4> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887SmallMolecule1753> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4740> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887SmallMolecule1444> .